Sheehan Lab

Advancing Sickle Cell Disease Research and Treatment

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Our Mission

The Sheehan Lab is dedicated to developing and improving therapies for individuals living with sickle cell disease. Our multifaceted approach combines genomics, clinical research, and innovative biomarker development to better understand and treat this complex disease.

Research Focus

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Gene-Based Therapies

Evaluating and improving gene therapy approaches for better patient outcomes. Identifying genetic factors and new drug targets to increase fetal hemoglobin levels.

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Pain Management

Investigating genetic factors in chronic pain development and biomarker research.

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Biomarker Development

Creating new methods to evaluate red cell function and therapy effectiveness.

Latest Research

Altered nasal and oral microbiomes define pediatric sickle cell disease.

Crouch AL, Severance BM, Creary S, et al.

mSphere (2025)

DOI PubMed
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Lab Life

Our team working together to advance sickle cell disease research

Sheehan Lab Group Photo
Lab Members at Conference
Student with Research Poster
Post-doc Presentation
Dr. Sheehan at Conference Panel
Lab Dinner
Mumbai Theme Night
Lab Outing